7C6I

Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in an open-liganded state bound to sophorose

7C6I の概要

• エントリーDOI: 10.2210/pdb7c6i/pdb
• 分子名称: Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, SULFUR DIOXIDE, ... (9 entities in total)
• 機能のキーワード: conformational dynamics, substrate-binding protein, induced-fit mechanism, two-step ligand binding, venus fly-trap mechanism, sugar binding protein
• 由来する生物種: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93210.59

構造登録者

Kanaujia, S.P.,Chandravanshi, M.,Samanta, R. (登録日: 2020-05-21, 公開日: 2020-09-16, 最終更新日: 2023-11-29)

• 主引用文献: Chandravanshi, M.,Samanta, R.,Kanaujia, S.P.; Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers.; J.Mol.Biol., 432:5711-5734, 2020; PubMed: 32866452; DOI: 10.1016/j.jmb.2020.08.021

実験手法

X-RAY DIFFRACTION (1.7 Å)