7C4O

Solution structure of the Orange domain from human protein HES1

7C4O の概要

• エントリーDOI: 10.2210/pdb7c4o/pdb
• 分子名称: Transcription factor HES-1 (1 entity in total)
• 機能のキーワード: dimer, solution structure, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 10710.28

構造登録者

Fan, J.S.,Nayak, A.,Swaminathan, K. (登録日: 2020-05-18, 公開日: 2021-05-19, 最終更新日: 2024-05-15)

• 主引用文献: Zhang, Q.,Wang, H.Y.,Nayak, A.,Nunez-Cruz, S.,Slupianek, A.,Liu, X.,Basappa, J.,Fan, J.S.,Chekol, S.,Nejati, R.,Bogusz, A.M.,Turner, S.D.,Swaminathan, K.,Wasik, M.A.; Induction of Transcriptional Inhibitor Hairy and Enhancer of Split Homolog-1 and the Related Repression of Tumor-Suppressor Thioredoxin-Interacting Protein Are Important Components of Cell-Transformation Program Imposed by Oncogenic Kinase Nucleophosmin-Anaplastic Lymphoma Kinase.; Am J Pathol, 2022; PubMed: 35640677; DOI: 10.1016/j.ajpath.2022.05.005

実験手法

SOLUTION NMR