7BZF

COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex

7BZF の概要

• エントリーDOI: 10.2210/pdb7bzf/pdb
• EMDBエントリー: 30252
• 分子名称: RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (6 entities in total)
• 機能のキーワード: covid-19, 2019-ncov, sars-cov-2, virus, rdrp, nsp12, nsp7, nsp8, rtc, cryo-em, viral protein, rna polymerase, drug target, antiviral, replication transcription complex, viral protein-rna complex, viral protein/rna
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 175832.92

構造登録者

Wang, Q.,Gao, Y.,Ji, W.,Mu, A.,Rao, Z. (登録日: 2020-04-27, 公開日: 2020-06-03, 最終更新日: 2024-03-27)

• 主引用文献: Wang, Q.,Wu, J.,Wang, H.,Gao, Y.,Liu, Q.,Mu, A.,Ji, W.,Yan, L.,Zhu, Y.,Zhu, C.,Fang, X.,Yang, X.,Huang, Y.,Gao, H.,Liu, F.,Ge, J.,Sun, Q.,Yang, X.,Xu, W.,Liu, Z.,Yang, H.,Lou, Z.,Jiang, B.,Guddat, L.W.,Gong, P.,Rao, Z.; Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.; Cell, 182:417-428.e13, 2020; PubMed: 32526208; DOI: 10.1016/j.cell.2020.05.034

実験手法

ELECTRON MICROSCOPY (3.26 Å)