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7BVG

Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.

Summary for 7BVG
Entry DOI10.2210/pdb7bvg/pdb
EMDB information30219
DescriptorIntegral membrane indolylacetylinositol arabinosyltransferase EmbA, Integral membrane indolylacetylinositol arabinosyltransferase EmbB, Meromycolate extension acyl carrier protein, ... (9 entities in total)
Functional Keywordsmycobacterium smegmatis, cell wall synthesis, drug target, ethambutol, arabinosyltransferase, emba, embb, embc, acyl carrier protein, arabinogalactan, lipoarabinomannan, drug resistance, transferase
Biological sourceMycolicibacterium smegmatis MC2 155
More
Total number of polymer chains3
Total formula weight251038.53
Authors
Zhang, L.,Zhao, Y.,Gao, Y.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z. (deposition date: 2020-04-10, release date: 2020-04-29, Last modification date: 2024-03-27)
Primary citationZhang, L.,Zhao, Y.,Gao, Y.,Wu, L.,Gao, R.,Zhang, Q.,Wang, Y.,Wu, C.,Wu, F.,Gurcha, S.S.,Veerapen, N.,Batt, S.M.,Zhao, W.,Qin, L.,Yang, X.,Wang, M.,Zhu, Y.,Zhang, B.,Bi, L.,Zhang, X.,Yang, H.,Guddat, L.W.,Xu, W.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z.
Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368:1211-1219, 2020
Cited by
PubMed: 32327601
DOI: 10.1126/science.aba9102
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

217705

건을2024-03-27부터공개중

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