7BTM
SDR protein/resistance protein NapW
Summary for 7BTM
Entry DOI | 10.2210/pdb7btm/pdb |
Descriptor | Short chain dehydrogenase (2 entities in total) |
Functional Keywords | sdr, rossmann, resistance, nadph, antibiotic, oxidoreductase |
Biological source | Streptomyces lusitanus |
Total number of polymer chains | 8 |
Total formula weight | 290027.18 |
Authors | Wen, W.H.,Tang, G.L. (deposition date: 2020-04-02, release date: 2021-10-06, Last modification date: 2023-11-29) |
Primary citation | Wen, W.H.,Zhang, Y.,Zhang, Y.Y.,Yu, Q.,Jiang, C.C.,Tang, M.C.,Pu, J.Y.,Wu, L.,Zhao, Y.L.,Shi, T.,Zhou, J.,Tang, G.L. Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics. Nat Commun, 12:7085-7085, 2021 Cited by PubMed: 34873166DOI: 10.1038/s41467-021-27404-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08311646214 Å) |
Structure validation
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