7BSX

SDR protein NapW-NADP

Summary for 7BSX

• Entry DOI: 10.2210/pdb7bsx/pdb
• Descriptor: Short chain dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: sdr, rossmann, resistance, nadph, antibiotic, oxidoreductase
• Biological source: Streptomyces lusitanus
• Total number of polymer chains: 8
• Total formula weight: 295974.42

Authors

Wen, W.H.,Tang, G.L. (deposition date: 2020-03-31, release date: 2021-10-06, Last modification date: 2023-11-29)

• Primary citation: Wen, W.H.,Zhang, Y.,Zhang, Y.Y.,Yu, Q.,Jiang, C.C.,Tang, M.C.,Pu, J.Y.,Wu, L.,Zhao, Y.L.,Shi, T.,Zhou, J.,Tang, G.L.; Reductive inactivation of the hemiaminal pharmacophore for resistance against tetrahydroisoquinoline antibiotics.; Nat Commun, 12:7085-7085, 2021; PubMed: 34873166; DOI: 10.1038/s41467-021-27404-3

Experimental method

X-RAY DIFFRACTION (2 Å)