7BSD

Complex structure of 1G5.3 Fab bound to ZIKV NS1c

Summary for 7BSD

• Entry DOI: 10.2210/pdb7bsd/pdb
• Descriptor: 1G5.3 Fab Heavy Chain, 1G5.3 Fab Light Chain, NS1C, ... (4 entities in total)
• Functional Keywords: zika virus, ns1, antibody, viral protein, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 137888.75

Authors

Song, H.,Qi, J.,Gao, F.G. (deposition date: 2020-03-30, release date: 2020-12-23, Last modification date: 2023-11-29)

• Primary citation: Modhiran, N.,Song, H.,Liu, L.,Bletchly, C.,Brillault, L.,Amarilla, A.A.,Xu, X.,Qi, J.,Chai, Y.,Cheung, S.T.M.,Traves, R.,Setoh, Y.X.,Bibby, S.,Scott, C.A.P.,Freney, M.E.,Newton, N.D.,Khromykh, A.A.,Chappell, K.J.,Muller, D.A.,Stacey, K.J.,Landsberg, M.J.,Shi, Y.,Gao, G.F.,Young, P.R.,Watterson, D.; A broadly protective antibody that targets the flavivirus NS1 protein.; Science, 371:190-194, 2021; PubMed: 33414219; DOI: 10.1126/science.abb9425

Experimental method

X-RAY DIFFRACTION (2.53 Å)