7BPZ

X-ray structure of human PPARalpha ligand binding domain-bezafibrate-SRC1 coactivator peptide co-crystals obtained by soaking

7BPZ の概要

• エントリーDOI: 10.2210/pdb7bpz/pdb
• 分子名称: Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, protein-ligand complex, ppar, transcription
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 66132.10

構造登録者

Kamata, S.,Ishikawa, R.,Akahane, M.,Oyama, T.,Ishii, I. (登録日: 2020-03-23, 公開日: 2020-11-11, 最終更新日: 2023-11-29)

• 主引用文献: Kamata, S.,Oyama, T.,Saito, K.,Honda, A.,Yamamoto, Y.,Suda, K.,Ishikawa, R.,Itoh, T.,Watanabe, Y.,Shibata, T.,Uchida, K.,Suematsu, M.,Ishii, I.; PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.; Iscience, 23:101727-101727, 2020; PubMed: 33205029; DOI: 10.1016/j.isci.2020.101727

実験手法

X-RAY DIFFRACTION (2.43 Å)