7BPV

r(GUGGGCCGAC)/d(GTCGGCCCAC) hybrid duplex structure

Summary for 7BPV

• Entry DOI: 10.2210/pdb7bpv/pdb
• Descriptor: RNA (5'-R(P*GP*UP*GP*GP*GP*CP*CP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*CP*CP*AP*C)-3'), SULFATE ION, ... (4 entities in total)
• Functional Keywords: g4c2 repeat, dna-rna hybrid, ggcc motif, a-like dna structure
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 6334.02

Authors

Wang, S.C.,Satange, R.B.,Hou, M.H. (deposition date: 2020-03-23, release date: 2021-03-03, Last modification date: 2023-11-29)

• Primary citation: Jhan, C.R.,Satange, R.,Wang, S.C.,Zeng, J.Y.,Horng, Y.C.,Jin, P.,Neidle, S.,Hou, M.H.; Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction.; Nucleic Acids Res., 49:9526-9538, 2021; PubMed: 33836081; DOI: 10.1093/nar/gkab227

Experimental method

X-RAY DIFFRACTION (1.781 Å)