7BPV
r(GUGGGCCGAC)/d(GTCGGCCCAC) hybrid duplex structure
Summary for 7BPV
Entry DOI | 10.2210/pdb7bpv/pdb |
Descriptor | RNA (5'-R(P*GP*UP*GP*GP*GP*CP*CP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*CP*CP*AP*C)-3'), SULFATE ION, ... (4 entities in total) |
Functional Keywords | g4c2 repeat, dna-rna hybrid, ggcc motif, a-like dna structure |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 6334.02 |
Authors | Wang, S.C.,Satange, R.B.,Hou, M.H. (deposition date: 2020-03-23, release date: 2021-03-03, Last modification date: 2023-11-29) |
Primary citation | Jhan, C.R.,Satange, R.,Wang, S.C.,Zeng, J.Y.,Horng, Y.C.,Jin, P.,Neidle, S.,Hou, M.H. Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction. Nucleic Acids Res., 49:9526-9538, 2021 Cited by PubMed: 33836081DOI: 10.1093/nar/gkab227 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.781 Å) |
Structure validation
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