7BOR

Structure of Pseudomonas aeruginosa CoA-bound OdaA

Summary for 7BOR

• Entry DOI: 10.2210/pdb7bor/pdb
• Descriptor: Probable enoyl-CoA hydratase/isomerase, COENZYME A (3 entities in total)
• Functional Keywords: pseudomonas aeruginosa, crotonase, isomerase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 2
• Total formula weight: 57910.30

Authors

Zhao, N.,Zhao, C.,Liu, L.,Li, T.,Li, C.,He, L.,Zhu, Y.,Song, Y.,Bao, R. (deposition date: 2020-03-19, release date: 2020-05-13, Last modification date: 2023-11-29)

Primary citation

Zhao, N.L.,Zhang, Q.Q.,Zhao, C.,Liu, L.,Li, T.,Li, C.C.,He, L.H.,Zhu, Y.B.,Song, Y.J.,Liu, H.X.,Bao, R.
Structural and molecular dynamic studies of Pseudomonas aeruginosa OdaA reveal the regulation role of a C-terminal hinge element.
Biochim Biophys Acta Gen Subj, 1865:129756-129756, 2020

PubMed Abstract: Crotonase superfamily members exhibit great catalytic diversity towards various acyl-CoA substrates. A common CoA moiety binding pattern is usually observed in this family, understanding the substrate-binding mechanism would facilitate the rational engineering of crotonases for improved properties.

PubMed: 33010351
DOI: 10.1016/j.bbagen.2020.129756

Experimental method

X-RAY DIFFRACTION (1.901 Å)