7BM9

Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide

Summary for 7BM9

• Entry DOI: 10.2210/pdb7bm9/pdb
• Descriptor: 14-3-3 protein sigma, VAL-ASN-LEU-SEP-ILE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: protein-peptide complex, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 28935.20

Authors

Centorrino, F.,Andlovic, B.,Ottmann, C. (deposition date: 2021-01-19, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Brink, H.J.,van Senten, J.R.,De Vries-van Leeuwen, I.J.,da Costa Pereira, D.,Piersma, S.R.,Jimenez, C.R.,Centorrino, F.,Ottmann, C.,Siderius, M.,Smit, M.J.,de Boer, A.H.; Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3.; Acs Chem.Biol., 17:2972-2978, 2022; PubMed: 36255265; DOI: 10.1021/acschembio.2c00299

Experimental method

X-RAY DIFFRACTION (1.8 Å)