7BL8

BAZ2A bromodomain in complex with the chemical probe BAZ2-ICR

Summary for 7BL8

• Entry DOI: 10.2210/pdb7bl8/pdb
• Related: 4XUB
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 4-[5-(1-methylpyrazol-4-yl)-3-[2-(1-methylpyrazol-4-yl)ethyl]imidazol-4-yl]benzenecarbonitrile (3 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 12738.33

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2021-01-18, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Chemical probes in the BAZ2A bromodomain; to be published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)