7BJ9

Structure of Sfh-I with 2-Mercaptomethyl-thiazolidine L-anti-1a

Summary for 7BJ9

• Entry DOI: 10.2210/pdb7bj9/pdb
• Descriptor: Beta-lactamase, ZINC ION, (2~{S},4~{R})-2-ethoxycarbonyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid, ... (5 entities in total)
• Functional Keywords: antibiotic resistance, lactamase, zinc, inhibitor, antimicrobial protein
• Biological source: Serratia fonticola
• Total number of polymer chains: 2
• Total formula weight: 53453.28

Authors

Hinchliffe, P.,Spencer, J. (deposition date: 2021-01-14, release date: 2021-08-25, Last modification date: 2024-01-31)

• Primary citation: Hinchliffe, P.,Moreno, D.M.,Rossi, M.A.,Mojica, M.F.,Martinez, V.,Villamil, V.,Spellberg, B.,Drusano, G.L.,Banchio, C.,Mahler, G.,Bonomo, R.A.,Vila, A.J.,Spencer, J.; 2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-beta-Lactamase Classes by Maintaining a Conserved Binding Mode.; Acs Infect Dis., 7:2697-2706, 2021; PubMed: 34355567; DOI: 10.1021/acsinfecdis.1c00194

Experimental method

X-RAY DIFFRACTION (1.21000590023 Å)