7BI5

Human CA II in complex with benzyl alcohol

Summary for 7BI5

• Entry DOI: 10.2210/pdb7bi5/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, phenylmethanol, ... (4 entities in total)
• Functional Keywords: benzyl alcohol, primary alcohol, inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29462.61

Authors

Alterio, V.,De Simone, G. (deposition date: 2021-01-12, release date: 2021-03-17, Last modification date: 2024-01-31)

• Primary citation: De Simone, G.,Bua, S.,Supuran, C.T.,Alterio, V.; Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule.; Biochem.Biophys.Res.Commun., 548:217-221, 2021; PubMed: 33647799; DOI: 10.1016/j.bbrc.2021.02.067

Experimental method

X-RAY DIFFRACTION (1.74 Å)