7BFZ

X-ray structure of human prostate-specific membrane antigen(PSMA) in complex with a inhibitor Glu-490

7BFZ の概要

• エントリーDOI: 10.2210/pdb7bfz/pdb
• 分子名称: Glutamate carboxypeptidase 2, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (14 entities in total)
• 機能のキーワード: glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen (psma); inhibitor, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 84540.56

構造登録者

Rakhimbekova, A.,Motlova, L.,Barinka, C. (登録日: 2021-01-05, 公開日: 2021-08-18, 最終更新日: 2024-01-31)

• 主引用文献: Zhang, J.,Rakhimbekova, A.,Duan, X.,Yin, Q.,Foss, C.A.,Fan, Y.,Xu, Y.,Li, X.,Cai, X.,Kutil, Z.,Wang, P.,Yang, Z.,Zhang, N.,Pomper, M.G.,Wang, Y.,Barinka, C.,Yang, X.; A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging.; Nat Commun, 12:5460-5460, 2021; PubMed: 34526506; DOI: 10.1038/s41467-021-25746-6

実験手法

X-RAY DIFFRACTION (1.73 Å)