7BER

SFX structure of the MyD88 TIR domain higher-order assembly (solved, rebuilt and refined using an identical protocol to the MicroED structure of the MyD88 TIR domain higher-order assembly)

7BER の概要

• エントリーDOI: 10.2210/pdb7ber/pdb
• 分子名称: Myeloid differentiation primary response protein MyD88 (1 entity in total)
• 機能のキーワード: sfx, serial femtosecond crystallography, myd88, tir domain, higher-order assembly, protein binding
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17833.85

構造登録者

Clabbers, M.T.B.,Holmes, S.,Muusse, T.W.,Vajjhala, P.,Thygesen, S.J.,Malde, A.K.,Hunter, D.J.B.,Croll, T.I.,Nanson, J.D.,Rahaman, M.H.,Aquila, A.,Hunter, M.S.,Liang, M.,Yoon, C.H.,Zhao, J.,Zatsepin, N.A.,Abbey, B.,Sierecki, E.,Gambin, Y.,Darmanin, C.,Kobe, B.,Xu, H.,Ve, T. (登録日: 2020-12-24, 公開日: 2021-03-10, 最終更新日: 2024-01-31)

• 主引用文献: Clabbers, M.T.B.,Holmes, S.,Muusse, T.W.,Vajjhala, P.R.,Thygesen, S.J.,Malde, A.K.,Hunter, D.J.B.,Croll, T.I.,Flueckiger, L.,Nanson, J.D.,Rahaman, M.H.,Aquila, A.,Hunter, M.S.,Liang, M.,Yoon, C.H.,Zhao, J.,Zatsepin, N.A.,Abbey, B.,Sierecki, E.,Gambin, Y.,Stacey, K.J.,Darmanin, C.,Kobe, B.,Xu, H.,Ve, T.; MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.; Nat Commun, 12:2578-2578, 2021; PubMed: 33972532; DOI: 10.1038/s41467-021-22590-6

実験手法

X-RAY DIFFRACTION (2.3 Å)