7B7B
BAZ2A bromodomain in complex with triazole compound MS04
Summary for 7B7B
Entry DOI | 10.2210/pdb7b7b/pdb |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2A, 5-ethyl-2-(3-methyl-1,2,3-triazol-4-yl)-1~{H}-benzimidazole (3 entities in total) |
Functional Keywords | four helical bundle, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 12591.14 |
Authors | Dalle Vedove, A.,Cazzanelli, G.,Sedykh, M.,Caflisch, A.,Lolli, G. (deposition date: 2020-12-10, release date: 2021-10-20, Last modification date: 2024-01-31) |
Primary citation | Dalle Vedove, A.,Cazzanelli, G.,Batiste, L.,Marchand, J.R.,Spiliotopoulos, D.,Corsi, J.,D'Agostino, V.G.,Caflisch, A.,Lolli, G. Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13:1434-1443, 2022 Cited by PubMed: 36105334DOI: 10.1021/acsmedchemlett.2c00173 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
Download full validation report