7B73
Insight into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.
Summary for 7B73
Entry DOI | 10.2210/pdb7b73/pdb |
Descriptor | Short-chain dehydrogenase/reductase SDR, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | thermostability, enantioselectivity changes, directed evolution, protein engineering, short-chain dehydrogenase/reductase enzyme superfamily, dehalogenase, lyase |
Biological source | gamma proteobacterium HTCC2207 |
Total number of polymer chains | 4 |
Total formula weight | 105845.48 |
Authors | Wessel, J.,Petrillo, G.,Estevez, M.,Bosh, S.,Seeger, M.,Dijkman, W.P.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A. (deposition date: 2020-12-09, release date: 2021-04-07, Last modification date: 2024-06-19) |
Primary citation | Wessel, J.,Petrillo, G.,Estevez-Gay, M.,Bosch, S.,Seeger, M.,Dijkman, W.P.,Iglesias-Fernandez, J.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A. Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2. Febs J., 288:4683-4701, 2021 Cited by PubMed: 33605544DOI: 10.1111/febs.15777 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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