7B73

Insight into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.

7B73 の概要

• エントリーDOI: 10.2210/pdb7b73/pdb
• 分子名称: Short-chain dehydrogenase/reductase SDR, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: thermostability, enantioselectivity changes, directed evolution, protein engineering, short-chain dehydrogenase/reductase enzyme superfamily, dehalogenase, lyase
• 由来する生物種: gamma proteobacterium HTCC2207
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 105845.48

構造登録者

Wessel, J.,Petrillo, G.,Estevez, M.,Bosh, S.,Seeger, M.,Dijkman, W.P.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A. (登録日: 2020-12-09, 公開日: 2021-04-07, 最終更新日: 2021-08-11)

• 主引用文献: Wessel, J.,Petrillo, G.,Estevez-Gay, M.,Bosch, S.,Seeger, M.,Dijkman, W.P.,Iglesias-Fernandez, J.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A.; Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.; Febs J., 288:4683-4701, 2021; PubMed: 33605544; DOI: 10.1111/febs.15777

実験手法

X-RAY DIFFRACTION (1.6 Å)