7B6G

Crystal structure of MurE from E.coli in complex with Z1675346324

This is a non-PDB format compatible entry.

Summary for 7B6G

• Entry DOI: 10.2210/pdb7b6g/pdb
• Descriptor: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, DIMETHYL SULFOXIDE, trans-3-[(2,6-dimethylpyrimidin-4-yl)(methyl)amino]cyclobutan-1-ol, ... (4 entities in total)
• Functional Keywords: udp-n-acetylmuramoyl-l-alanyl-d-glutamate-2, 6-diaminopimelate ligase cell wall biosynthesis ligase drug target, structural genomics, structural genomics consortium, sgc, biosynthetic protein, fragment screening
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 107350.55

Authors

Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-07, release date: 2021-01-13, Last modification date: 2024-01-31)

• Primary citation: Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.; Crystal structure of MurE from E.coli; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.937 Å)