7B6F
GSK3-beta in complex with compound (S)-5c
Summary for 7B6F
Entry DOI | 10.2210/pdb7b6f/pdb |
Descriptor | Glycogen synthase kinase-3 beta, 3-[(3~{S})-3-[(7-chloranyl-9~{H}-pyrimido[4,5-b]indol-4-yl)-methyl-amino]piperidin-1-yl]propanenitrile, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | kinase inhibitors, structure-based drug design, gsk3-beta inhibitor, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42374.87 |
Authors | Tesch, R.,Andreev, S.,Koch, P.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-07, release date: 2020-12-16, Last modification date: 2024-01-31) |
Primary citation | Tesch, R.,Andreev, S.,Koch, P.,Knapp, S.,Structural Genomics Consortium (SGC) GSK3-beta in complex with compound (S)-5c To be published, |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report