7B6C

BK Polyomavirus VP1 pentamer fusion with long C-terminal extended arm

This is a non-PDB format compatible entry.

Summary for 7B6C

• Entry DOI: 10.2210/pdb7b6c/pdb
• Descriptor: Major capsid protein VP1,Major capsid protein VP1, DIMETHYL SULFOXIDE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: viral protein, polyomavirus, capsid protein, chimera
• Biological source: BK polyomavirus (BKPyV); More
• Total number of polymer chains: 10
• Total formula weight: 313487.89

Authors

Osipov, E.M.,Beelen, S.,Strelkov, S.V. (deposition date: 2020-12-07, release date: 2022-06-22, Last modification date: 2024-01-31)

• Primary citation: Osipov, E.M.,Munawar, A.H.,Beelen, S.,Fearon, D.,Douangamath, A.,Wild, C.,Weeks, S.D.,Van Aerschot, A.,von Delft, F.,Strelkov, S.V.; Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.; Rsc Chem Biol, 3:1013-1027, 2022; PubMed: 35974998; DOI: 10.1039/d2cb00052k

Experimental method

X-RAY DIFFRACTION (2.484 Å)