7B62

Crystal structure of SARS-CoV-2 spike protein N-terminal domain in complex with biliverdin

7B62 の概要

• エントリーDOI: 10.2210/pdb7b62/pdb
• 分子名称: Spike glycoprotein, BILIVERDINE IX ALPHA, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: sarscov2, covid19, biliverdin, coronavirus, ntd, green, spike, glycoprotein, s1, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39920.94

構造登録者

Pye, V.E.,Rosa, A.,Roustan, C.,Cherepanov, P. (登録日: 2020-12-07, 公開日: 2021-04-28, 最終更新日: 2024-01-31)

• 主引用文献: Rosa, A.,Pye, V.E.,Graham, C.,Muir, L.,Seow, J.,Ng, K.W.,Cook, N.J.,Rees-Spear, C.,Parker, E.,Dos Santos, M.S.,Rosadas, C.,Susana, A.,Rhys, H.,Nans, A.,Masino, L.,Roustan, C.,Christodoulou, E.,Ulferts, R.,Wrobel, A.G.,Short, C.E.,Fertleman, M.,Sanders, R.W.,Heaney, J.,Spyer, M.,Kjaer, S.,Riddell, A.,Malim, M.H.,Beale, R.,MacRae, J.I.,Taylor, G.P.,Nastouli, E.,van Gils, M.J.,Rosenthal, P.B.,Pizzato, M.,McClure, M.O.,Tedder, R.S.,Kassiotis, G.,McCoy, L.E.,Doores, K.J.,Cherepanov, P.; SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.; Sci Adv, 7:-, 2021; PubMed: 33888467; DOI: 10.1126/sciadv.abg7607

実験手法

X-RAY DIFFRACTION (1.82 Å)