7B5K

E. coli 70S containing suppressor tRNA in the A-site stabilized by a Negamycin analogue and P-site tRNA-nascent chain.

This is a non-PDB format compatible entry.

Summary for 7B5K

• Entry DOI: 10.2210/pdb7b5k/pdb
• EMDB information: 12035
• Descriptor: 23S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
• Functional Keywords: cryo-em, 70s, p-site trna, e-site trna, erythromycin, n6-(3aminopropyl)-negamycin, antibiotics, ribosome
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 57
• Total formula weight: 2196774.89

Authors

Albers, S.,Beckert, B.,Matthies, M.,Schuster, R.,Riedner, M.,Seuring, C.,Sanyal, S.,Torda, A.,Wilson, N.D.,Ignatova, Z. (deposition date: 2020-12-03, release date: 2021-05-26, Last modification date: 2024-04-24)

• Primary citation: Albers, S.,Beckert, B.,Wilson, N.D.,Ignatova, Z.; Harnessing evolutionarily flexibility in tRNAs to maximize nonsense suppression activities; Nat Commun, 2021

Experimental method

ELECTRON MICROSCOPY (2.9 Å)