7B4X
Notum complex with ARUK3002697
Summary for 7B4X
Entry DOI | 10.2210/pdb7b4x/pdb |
Descriptor | Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, DIMETHYL SULFOXIDE, ... (6 entities in total) |
Functional Keywords | notum inhibitor complex, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 44980.56 |
Authors | Jones, E.Y.,Fish, P. (deposition date: 2020-12-02, release date: 2022-01-12, Last modification date: 2024-01-31) |
Primary citation | Zhao, Y.,Mahy, W.,Willis, N.J.,Woodward, H.L.,Steadman, D.,Bayle, E.D.,Atkinson, B.N.,Sipthorp, J.,Vecchia, L.,Ruza, R.R.,Harlos, K.,Jeganathan, F.,Constantinou, S.,Costa, A.,Kjaer, S.,Bictash, M.,Salinas, P.C.,Whiting, P.,Vincent, J.P.,Fish, P.V.,Jones, E.Y. Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13:2060-2077, 2022 Cited by PubMed: 35731924DOI: 10.1021/acschemneuro.2c00325 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)