7B2Z
Notum complex with ARUK3003907
Summary for 7B2Z
Entry DOI | 10.2210/pdb7b2z/pdb |
Descriptor | Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | notum inhibitor, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 44619.30 |
Authors | Zhao, Y.,Jone, E.Y. (deposition date: 2020-11-28, release date: 2021-08-04, Last modification date: 2024-01-31) |
Primary citation | Zhao, Y.,Svensson, F.,Steadman, D.,Frew, S.,Monaghan, A.,Bictash, M.,Moreira, T.,Chalk, R.,Lu, W.,Fish, P.V.,Jones, E.Y. Structural Insights into Notum Covalent Inhibition. J.Med.Chem., 64:11354-11363, 2021 Cited by PubMed: 34292747DOI: 10.1021/acs.jmedchem.1c00701 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.24 Å) |
Structure validation
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