7B1J
Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Summary for 7B1J
Entry DOI | 10.2210/pdb7b1j/pdb |
Descriptor | Mitotic spindle assembly checkpoint protein MAD1, Mitotic checkpoint serine/threonine-protein kinase BUB1 (2 entities in total) |
Functional Keywords | mad1, bub1, spindle assembly checkpoint, mitotic checkpoint complex, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 33810.29 |
Authors | Fischer, E.,Bellini, D.,Barford, D. (deposition date: 2020-11-25, release date: 2021-03-17, Last modification date: 2024-01-31) |
Primary citation | Fischer, E.S.,Yu, C.W.H.,Bellini, D.,McLaughlin, S.H.,Orr, C.M.,Wagner, A.,Freund, S.M.V.,Barford, D. Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1. Embo Rep., 22:e52242-e52242, 2021 Cited by PubMed: 34013668DOI: 10.15252/embr.202052242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)