7B1H
Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Summary for 7B1H
| Entry DOI | 10.2210/pdb7b1h/pdb |
| Descriptor | Mitotic spindle assembly checkpoint protein MAD1, Mitotic checkpoint serine/threonine-protein kinase BUB1 (3 entities in total) |
| Functional Keywords | mad1, bub1, spindle assembly checkpoint, mitotic checkpoint complex, cell cycle |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 67940.49 |
| Authors | Fischer, E.,Bellini, D.,Barford, D. (deposition date: 2020-11-24, release date: 2021-03-17, Last modification date: 2024-01-31) |
| Primary citation | Fischer, E.S.,Yu, C.W.H.,Bellini, D.,McLaughlin, S.H.,Orr, C.M.,Wagner, A.,Freund, S.M.V.,Barford, D. Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1. Embo Rep., 22:e52242-e52242, 2021 Cited by PubMed: 34013668DOI: 10.15252/embr.202052242 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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