7B1H

Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain

7B1H の概要

• エントリーDOI: 10.2210/pdb7b1h/pdb
• 分子名称: Mitotic spindle assembly checkpoint protein MAD1, Mitotic checkpoint serine/threonine-protein kinase BUB1 (3 entities in total)
• 機能のキーワード: mad1, bub1, spindle assembly checkpoint, mitotic checkpoint complex, cell cycle
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 67940.49

構造登録者

Fischer, E.,Bellini, D.,Barford, D. (登録日: 2020-11-24, 公開日: 2021-03-17, 最終更新日: 2024-01-31)

• 主引用文献: Fischer, E.S.,Yu, C.W.H.,Bellini, D.,McLaughlin, S.H.,Orr, C.M.,Wagner, A.,Freund, S.M.V.,Barford, D.; Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.; Embo Rep., 22:e52242-e52242, 2021; PubMed: 34013668; DOI: 10.15252/embr.202052242

実験手法

X-RAY DIFFRACTION (2.4 Å)