7AZA

Perdeuterated E65Q-TIM complexed with PHOSPHOGLYCOLOHYDROXAMATE

Summary for 7AZA

• Entry DOI: 10.2210/pdb7aza/pdb
• Descriptor: Triosephosphate isomerase, PHOSPHOGLYCOLOHYDROXAMIC ACID (3 entities in total)
• Functional Keywords: isomerase, glycolysis, tim, triosephosphate isomerase, transition state, perdeuteration
• Biological source: Leishmania mexicana
• Total number of polymer chains: 1
• Total formula weight: 27379.28

Authors

Kelpsas, V.,Caldararu, O.,von Wachenfeldt, C.,Oksanen, E. (deposition date: 2020-11-16, release date: 2021-07-28)

• Primary citation: Kelpsas, V.,Caldararu, O.,Blakeley, M.P.,Coquelle, N.,Wierenga, R.K.,Ryde, U.,von Wachenfeldt, C.,Oksanen, E.; Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps.; Iucrj, 8:633-643, 2021; PubMed: 34258011; DOI: 10.1107/S2052252521004619

Experimental method

NEUTRON DIFFRACTION (1.8 Å)
X-RAY DIFFRACTION (1.1 Å)