7ARA
Rhinovirus A2 2A protease in complex with zVAM.fmk
Summary for 7ARA
Entry DOI | 10.2210/pdb7ara/pdb |
Descriptor | 2A protease, (phenylmethyl) ~{N}-[(2~{R})-3-methyl-1-[[(2~{S})-1-[[(3~{S})-1-methylsulfanyl-4-oxidanylidene-pentan-3-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-butan-2-yl]carbamate, ZINC ION, ... (5 entities in total) |
Functional Keywords | chymotrypsin-like cysteine protease, rhinoviral 2a protease, zvam.fmk, viral protein |
Biological source | Human rhinovirus 2 (HRV-2) |
Total number of polymer chains | 2 |
Total formula weight | 33486.31 |
Authors | Deutschmann-Olek, K.M.,Skern, T.,Bezerra, G.A.,Yue, W.W. (deposition date: 2020-10-23, release date: 2021-07-28, Last modification date: 2024-01-31) |
Primary citation | Deutschmann-Olek, K.M.,Yue, W.W.,Bezerra, G.A.,Skern, T. Defining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk. Virology, 562:128-141, 2021 Cited by PubMed: 34315103DOI: 10.1016/j.virol.2021.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.243 Å) |
Structure validation
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