7AQZ

Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB14)

Summary for 7AQZ

Entry DOI	10.2210/pdb7aqz/pdb
Descriptor	Variant surface glycoprotein MITAT 1.2, Nanobody VSG2(NB14), alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	variant surface glycoprotein, epitope mapping, immune evasion, membrane protein
Biological source	Lama glama (Llama) More
Total number of polymer chains	4
Total formula weight	108534.53
Authors	Stebbins, C.E.,Hempelmann, A.,VanStraaten, M. (deposition date: 2020-10-23, release date: 2021-11-03, Last modification date: 2024-02-07)
Primary citation	Hempelmann, A.,Hartleb, L.,van Straaten, M.,Hashemi, H.,Zeelen, J.P.,Bongers, K.,Papavasiliou, F.N.,Engstler, M.,Stebbins, C.E.,Jones, N.G. Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome. Cell Rep, 37:109923-109923, 2021 Cited by PubMed: 34731611 DOI: 10.1016/j.celrep.2021.109923 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation