7AQX

Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB9)

7AQX の概要

• エントリーDOI: 10.2210/pdb7aqx/pdb
• 分子名称: Variant surface glycoprotein MITAT 1.2, Nanobody VSG2(NB9), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: variant surface glycoprotein, epitope mapping, immune evasion, membrane protein
• 由来する生物種: Lama glama (Llama); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 110706.69

構造登録者

Stebbins, C.E.,Hempelmann, A. (登録日: 2020-10-23, 公開日: 2021-11-03, 最終更新日: 2024-02-07)

• 主引用文献: Hempelmann, A.,Hartleb, L.,van Straaten, M.,Hashemi, H.,Zeelen, J.P.,Bongers, K.,Papavasiliou, F.N.,Engstler, M.,Stebbins, C.E.,Jones, N.G.; Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.; Cell Rep, 37:109923-109923, 2021; PubMed: 34731611; DOI: 10.1016/j.celrep.2021.109923

実験手法

X-RAY DIFFRACTION (1.499 Å)