7AQ1

Crystal structure of human mature meprin beta in complex with the specific inhibitor MWT-S-270

7AQ1 の概要

• エントリーDOI: 10.2210/pdb7aq1/pdb
• 分子名称: Meprin B subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: astacin protease, metalloproteinase, zn dependent, sheddase, gamma secretase, inhbibitor bound meprin beta holoenzyme, intermolecular disulfide bridge homodimer, glycoprotein, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 127877.33

構造登録者

Linnert, M.,Parthier, C.,Fritz, C. (登録日: 2020-10-20, 公開日: 2021-03-03, 最終更新日: 2024-01-31)

• 主引用文献: Linnert, M.,Fritz, C.,Jager, C.,Schlenzig, D.,Ramsbeck, D.,Kleinschmidt, M.,Wermann, M.,Demuth, H.U.,Parthier, C.,Schilling, S.; Structure and Dynamics of Meprin beta in Complex with a Hydroxamate-Based Inhibitor.; Int J Mol Sci, 22:-, 2021; PubMed: 34073350; DOI: 10.3390/ijms22115651

実験手法