7AMH

SmBRD3(2), Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM-A-33, an iBET726 analogue

Summary for 7AMH

• Entry DOI: 10.2210/pdb7amh/pdb
• Descriptor: Putative bromodomain-containing protein 3, brd3, 4-{(2S, 4R)-1-acetyl-4-[(1-benzothiophen-6-yl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl}benzoic acid (3 entities in total)
• Functional Keywords: bromo domain, methyllysine binding, epigenetic reader domain, inhibitor, complex, protein binding
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 2
• Total formula weight: 30972.97

Authors

McArdle, D.,Schiedel, M.,McDonough, M.A.,Conway, S.J. (deposition date: 2020-10-08, release date: 2021-10-20, Last modification date: 2024-01-31)

• Primary citation: McArdle, D.J.B.,Schiedel, M.,McDonough, M.A.,Conway, S.J.; SBM3_2, Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM1, an iBET726 analogue; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.863 Å)