7AMH

SmBRD3(2), Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM-A-33, an iBET726 analogue

7AMH の概要

• エントリーDOI: 10.2210/pdb7amh/pdb
• 分子名称: Putative bromodomain-containing protein 3, brd3, 4-{(2S, 4R)-1-acetyl-4-[(1-benzothiophen-6-yl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl}benzoic acid (3 entities in total)
• 機能のキーワード: bromo domain, methyllysine binding, epigenetic reader domain, inhibitor, complex, protein binding
• 由来する生物種: Schistosoma mansoni (Blood fluke)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 30972.97

構造登録者

McArdle, D.,Schiedel, M.,McDonough, M.A.,Conway, S.J. (登録日: 2020-10-08, 公開日: 2021-10-20, 最終更新日: 2024-01-31)

• 主引用文献: McArdle, D.J.B.,Schiedel, M.,McDonough, M.A.,Conway, S.J.; SBM3_2, Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM1, an iBET726 analogue; To Be Published,

実験手法

X-RAY DIFFRACTION (1.863 Å)