7A7G

Soluble epoxide hydrolase in complex with TK90

7A7G の概要

• エントリーDOI: 10.2210/pdb7a7g/pdb
• 分子名称: Bifunctional epoxide hydrolase 2, (2~{R})-2-[[4-[[4-methoxy-2-(trifluoromethyl)phenyl]methylcarbamoyl]phenyl]methyl]butanoic acid (3 entities in total)
• 機能のキーワード: complex, structural genomics, structural genomics consortium, sgc, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80115.86

構造登録者

Ni, X.,Kramer, J.S.,Kirchner, T.,Proschak, E.,Chaikuad, A.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2020-08-28, 公開日: 2021-08-04, 最終更新日: 2024-01-31)

• 主引用文献: Hartmann, M.,Bibli, S.I.,Tews, D.,Ni, X.,Kircher, T.,Kramer, J.S.,Kilu, W.,Heering, J.,Hernandez-Olmos, V.,Weizel, L.,Scriba, G.K.E.,Krait, S.,Knapp, S.,Chaikuad, A.,Merk, D.,Fleming, I.,Fischer-Posovszky, P.,Proschak, E.; Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPAR gamma Modulator.; J.Med.Chem., 64:2815-2828, 2021; PubMed: 33620196; DOI: 10.1021/acs.jmedchem.0c02063

実験手法

X-RAY DIFFRACTION (2.4 Å)