7A74
Structure of G132N BlaC from Mycobacterium tuberculosis
Summary for 7A74
Entry DOI | 10.2210/pdb7a74/pdb |
Descriptor | Beta-lactamase, GLYCEROL, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | blac, beta-lactamase, mycobacterium tuberculosis, hydrolase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 1 |
Total formula weight | 29880.11 |
Authors | Chikunova, A.,Ahmad, M.U.,Perrakis, A.,Ubbink, M. (deposition date: 2020-08-27, release date: 2021-05-19, Last modification date: 2024-01-31) |
Primary citation | Elings, W.,Chikunova, A.,van Zanten, D.B.,Drenth, R.,Ahmad, M.U.D.,Blok, A.J.,Timmer, M.,Perrakis, A.,Ubbink, M. Two beta-Lactamase Variants with Reduced Clavulanic Acid Inhibition Display Different Millisecond Dynamics. Antimicrob.Agents Chemother., 65:e0262820-e0262820, 2021 Cited by PubMed: 34031049DOI: 10.1128/AAC.02628-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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