7A54

Two copies of the catalytic domain of NanA sialidase from Streptococcus pneumoniae juxtaposed in the P212121 space group, in complex with DANA

7A54 の概要

• エントリーDOI: 10.2210/pdb7a54/pdb
• 分子名称: Sialidase A, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID (3 entities in total)
• 機能のキーワード: sialidase, catalytic domain, dana, structural protein
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 112865.70

構造登録者

Bridot, C.,Bouckaert, J. (登録日: 2020-08-20, 公開日: 2020-11-18, 最終更新日: 2024-01-31)

• 主引用文献: Assailly, C.,Bridot, C.,Saumonneau, A.,Lottin, P.,Roubinet, B.,Krammer, E.M.,Francois, F.,Vena, F.,Landemarre, L.,Alvarez Dorta, D.,Deniaud, D.,Grandjean, C.,Tellier, C.,Pascual, S.,Montembault, V.,Fontaine, L.,Daligault, F.,Bouckaert, J.,Gouin, S.G.; Polyvalent Transition-State Analogues of Sialyl Substrates Strongly Inhibit Bacterial Sialidases*.; Chemistry, 27:3142-3150, 2021; PubMed: 33150981; DOI: 10.1002/chem.202004672

実験手法

X-RAY DIFFRACTION (2.7 Å)