7A41

MALT1 in complex with a NVS-MALT1 chemical probe

Summary for 7A41

• Entry DOI: 10.2210/pdb7a41/pdb
• Descriptor: Mucosa-associated lymphoid tissue lymphoma translocation protein 1, ~{N}-[(1~{S})-1-[4-[[2-chloranyl-7-[(1~{S})-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]amino]phenyl]-2,2,2-tris(fluoranyl)ethyl]-~{N}-methyl-1,1-bis(oxidanylidene)thiane-4-carboxamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: allosteric inhibitor, complex, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 92584.93

Authors

Renatus, M. (deposition date: 2020-08-19, release date: 2020-12-02, Last modification date: 2024-01-31)

• Primary citation: Renatus, M.; MALT1 in complex with a NVS-MALT1 chemical probe; Not Published,

Experimental method

X-RAY DIFFRACTION (2.13 Å)