7A21

Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2158

7A21 の概要

• エントリーDOI: 10.2210/pdb7a21/pdb
• 分子名称: Activin receptor type I, 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: kinase, inhibitor complex, receptor, signaling protein, bmp
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70192.72

構造登録者

Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (登録日: 2020-08-14, 公開日: 2020-09-16, 最終更新日: 2024-01-31)

• 主引用文献: Adamson, R.J.,Williams, E.P.,Smil, D.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N.; Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2153; To Be Published,

実験手法

X-RAY DIFFRACTION (2.14 Å)