7ZAK
Crystal structure of HLA-DP (DPA1*02:01-DPB1*01:01) in complex with a peptide
Summary for 7ZAK
Entry DOI | 10.2210/pdb7zak/pdb |
Descriptor | MHC class II HLA-DP alpha chain (DPA1*02:01), MHC class II HLA-DP beta chain (DPB1*01:01), Synthetic peptide, ... (7 entities in total) |
Functional Keywords | hla class ii, human leukocyte antigen class ii, mhc class ii, major histocompatibility complex class ii, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 62831.16 |
Authors | Racle, J.,Guillaume, P.,Larabi, A.,Lau, K.,Pojer, F.,Gfeller, D. (deposition date: 2022-03-22, release date: 2023-03-29, Last modification date: 2024-02-07) |
Primary citation | Racle, J.,Guillaume, P.,Schmidt, J.,Michaux, J.,Larabi, A.,Lau, K.,Perez, M.A.S.,Croce, G.,Genolet, R.,Coukos, G.,Zoete, V.,Pojer, F.,Bassani-Sternberg, M.,Harari, A.,Gfeller, D. Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes. Immunity, 56:1359-1375.e13, 2023 Cited by PubMed: 37023751DOI: 10.1016/j.immuni.2023.03.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.62 Å) |
Structure validation
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