7YSX
Crystal structure of PDE4D complexed with licoisoflavone A
Summary for 7YSX
Entry DOI | 10.2210/pdb7ysx/pdb |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | pde4d, complex, licoisoflavone a, inhibitor, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 81391.18 |
Authors | |
Primary citation | Xu, H.,Li, S.,Liu, J.,Cheng, J.,Kang, L.,Li, W.,Zhong, Y.,Wei, C.,Fu, L.,Qi, J.,Zhang, Y.,You, M.,Zhou, Z.,Zhang, C.,Su, H.,Yao, S.,Zhou, Z.,Shi, Y.,Deng, R.,Lv, Q.,Li, F.,Qi, F.,Chen, J.,Zhang, S.,Ma, X.,Xu, Z.,Li, S.,Xu, Y.,Peng, K.,Shi, Y.,Jiang, H.,Gao, G.F.,Huang, L. Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19. Proc.Natl.Acad.Sci.USA, 120:e2301775120-e2301775120, 2023 Cited by PubMed: 37094153DOI: 10.1073/pnas.2301775120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
Download full validation report