7YNJ
Structure of human SGLT2-MAP17 complex bound with substrate AMG in the occluded conformation
Summary for 7YNJ
Entry DOI | 10.2210/pdb7ynj/pdb |
EMDB information | 33963 |
Descriptor | Sodium/glucose cotransporter 2, PDZK1-interacting protein 1, methyl alpha-D-glucopyranoside (3 entities in total) |
Functional Keywords | glucose transporter, sglt, sodium glucose transporter, membrane protein, protein transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 85378.60 |
Authors | |
Primary citation | Cui, W.,Niu, Y.,Sun, Z.,Liu, R.,Chen, L. Structures of human SGLT in the occluded state reveal conformational changes during sugar transport. Nat Commun, 14:2920-2920, 2023 Cited by PubMed: 37217492DOI: 10.1038/s41467-023-38720-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.33 Å) |
Structure validation
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