7YMZ

Cryo-EM structure of MERS-CoV spike protein, intermediate conformation

Summary for 7YMZ

• Entry DOI: 10.2210/pdb7ymz/pdb
• EMDB information: 33948
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: mers-cov, spike, glycoprotein, viral protein
• Biological source: Human betacoronavirus 2c EMC/2012
• Total number of polymer chains: 3
• Total formula weight: 464647.18

Authors

Hsu, S.T.D.,Chang, N.E.,Weng, Z.W.,Yang, T.J.,Draczkowski, P. (deposition date: 2022-07-29, release date: 2023-08-09, Last modification date: 2024-09-04)

• Primary citation: Tsai, Y.X.,Chang, N.E.,Reuter, K.,Chang, H.T.,Yang, T.J.,von Bulow, S.,Sehrawat, V.,Zerrouki, N.,Tuffery, M.,Gecht, M.,Grothaus, I.L.,Colombi Ciacchi, L.,Wang, Y.S.,Hsu, M.F.,Khoo, K.H.,Hummer, G.,Hsu, S.D.,Hanus, C.,Sikora, M.; Rapid simulation of glycoprotein structures by grafting and steric exclusion of glycan conformer libraries.; Cell, 187:1296-1311.e26, 2024; PubMed: 38428397; DOI: 10.1016/j.cell.2024.01.034

Experimental method

ELECTRON MICROSCOPY (4.39 Å)