7YKE

Crystal structure of chondroitin ABC lyase I in complex with chondroitin disaccharide 4,6-sulfate

Summary for 7YKE

Entry DOI	10.2210/pdb7yke/pdb
Descriptor	Chondroitin sulfate ABC endolyase, 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4,6-di-O-sulfo-beta-D-galactopyranose, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	complex, polysaccharide lyase family 8, carbohydrate-binding, lyase
Biological source	Proteus vulgaris
Total number of polymer chains	1
Total formula weight	116319.58
Authors	Takashima, M.,Watanabe, I.,Miyanaga, A.,Eguchi, T. (deposition date: 2022-07-22, release date: 2022-11-30, Last modification date: 2023-11-29)
Primary citation	Watanabe, I.,Miyanaga, A.,Hoshi, H.,Suzuki, K.,Eguchi, T. Biochemical and crystallographic assessments of the effect of 4,6-O-disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity. Febs J., 290:2379-2393, 2023 Cited by PubMed: 36478634 DOI: 10.1111/febs.16685 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation