7YDI

SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region

This is a non-PDB format compatible entry.

Summary for 7YDI

• Entry DOI: 10.2210/pdb7ydi/pdb
• EMDB information: 33748
• Descriptor: Processed angiotensin-converting enzyme 2, Spike protein S1, Heavy chain of R1-32, ... (6 entities in total)
• Functional Keywords: antibodies, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 138566.27

Authors

Liu, B.,Gao, X.,Li, Z.,Chen, X.,He, J.,Chen, L.,Xiong, X. (deposition date: 2022-07-04, release date: 2022-08-24, Last modification date: 2023-07-26)

• Primary citation: He, P.,Liu, B.,Gao, X.,Yan, Q.,Pei, R.,Sun, J.,Chen, Q.,Hou, R.,Li, Z.,Zhang, Y.,Zhao, J.,Sun, H.,Feng, B.,Wang, Q.,Yi, H.,Hu, P.,Li, P.,Zhang, Y.,Chen, Z.,Niu, X.,Zhong, X.,Jin, L.,Liu, X.,Qu, K.,Ciazynska, K.A.,Carter, A.P.,Briggs, J.A.G.,Chen, J.,Liu, J.,Chen, X.,He, J.,Chen, L.,Xiong, X.; SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.; Nat Microbiol, 7:1635-1649, 2022; PubMed: 36151403; DOI: 10.1038/s41564-022-01235-4

Experimental method

ELECTRON MICROSCOPY (3.98 Å)