7YCL

Crystal structure of SARS-CoV-2 Spike RBD in complex with IS-9A Fab

Summary for 7YCL

Entry DOI	10.2210/pdb7ycl/pdb
Descriptor	IS-9A Fab heavy chain, IS-9A Fab light chain, Spike protein S1, ... (5 entities in total)
Functional Keywords	antibody, sars-cov-2, spike, rbd, class 4, viral protein-immune system complex, viral protein/immune system
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	141924.12
Authors	Mohapatra, A.,Chen, X. (deposition date: 2022-07-01, release date: 2023-02-01, Last modification date: 2023-11-29)
Primary citation	Huang, K.A.,Chen, X.,Mohapatra, A.,Nguyen, H.T.V.,Schimanski, L.,Tan, T.K.,Rijal, P.,Vester, S.K.,Hills, R.A.,Howarth, M.,Keeffe, J.R.,Cohen, A.A.,Kakutani, L.M.,Wu, Y.M.,Shahed-Al-Mahmud, M.,Chou, Y.C.,Bjorkman, P.J.,Townsend, A.R.,Ma, C. Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14:311-311, 2023 Cited by PubMed: 36658148 DOI: 10.1038/s41467-023-35949-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.13 Å)

Structure validation