7YAD

Cryo-EM structure of S309-RBD-RBD-S309 in the S309-bound Omicron spike protein (local refinement)

Summary for 7YAD

Entry DOI	10.2210/pdb7yad/pdb
EMDB information	33709
Descriptor	S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, Spike protein S1, ... (4 entities in total)
Functional Keywords	sars-cov-2, omicron, spike protein, s309 antibody, viral protein, immune system-viral protein complex, immune system/viral protein
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	97681.27
Authors	Zhao, Z.N.,Xie, Y.F.,Qi, J.X.,Gao, F. (deposition date: 2022-06-27, release date: 2022-08-31, Last modification date: 2022-09-07)
Primary citation	Zhao, Z.,Zhou, J.,Tian, M.,Huang, M.,Liu, S.,Xie, Y.,Han, P.,Bai, C.,Han, P.,Zheng, A.,Fu, L.,Gao, Y.,Peng, Q.,Li, Y.,Chai, Y.,Zhang, Z.,Zhao, X.,Song, H.,Qi, J.,Wang, Q.,Wang, P.,Gao, G.F. Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape. Nat Commun, 13:4958-4958, 2022 Cited by PubMed: 36002453 DOI: 10.1038/s41467-022-32665-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.66 Å)

Structure validation